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At the American Chemical Society’s national meeting today, March 23, scientists reported on a “miracle dog”, a Bichon named Oscar. After being treated with a new drug for an aggressive form of anal sac adenocarcinoma, Oscar is in remission and walking around after only two weeks. Without any negative side effects! This result on a dog given at best a few months to live is a miracle. Three other dogs have had the drug, all with positive results and very limited toxicity beyond the tumor site.
As reported by ScienceDaily, Dr. Joseph Bauer noted that theirs is one of the few research groups offering to treat dogs with cancer who have no other options of treatment. This gives not only dog owners hope, but the delivery mechanism for the drug Nitrosylcobalamin (NO-Cbl), described as a “Trojan Horse” to cancer cells, has probable human application. Bauer’s team at Cleveland Clinic plans to treat a total of 10 dogs and, given the genetic similarities between dogs and humans, this should accelerate FDA fast track approval for a dual dog and human cancer drug trial.
Bauer explained how scientists have been trying to find an “in” to cancer cells using the B-12 vitamin as a foil since the 1950’s. Cancer cells form 100x the B-12 receptors than regular cells to accommodate their accelerated rate of growth, making a B-12 delivery system highly effective. The dream of a targeted delivery system to attack a tumor and kill it from the inside means no toxic side effects. None of the debilitating effects evidenced by radiation and chemotherapy treatments have been recorded.
Now how great is that?
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Scrivo dall'Italia, prima di voi ho scritto a moltissime altre persone, giornali, Dr. Bauer, Cleveland Clinic, veterinari Protezione animali (tutti nella zona di Cleveland).
Mi ha risposto di Dr. Bauer che però attualmente non ha l'NO-cbl.
La NO-cbl è sperimentata alla Cleveland Clinic, ma io non riesco a mettermi in contatto con il trial di ricerca.
Il mio cane sta male, io non ho molto tempo per provare a curarlo.
In Italia mi dicono che non si può fare niente: lui ha un cancro sotto ad una ascella che gli impedisce di camminare correttamente e di stare in piedi.
Vi prego aiutatemi.
Anna
If Dr Bauer told you there were no open trials for your dog to enter, his information is the best you can get. He was the lead scientist on this work. I know he said he was only taking ten dogs, that's 10, for his no side effect trial experiment on dogs who had no other hope. I am certain those places were taken immediately; this was offered back in March this year.
I am not aware of any news of new trials. You could talk to other veterinary cancer specialists in the US to see what if any help they might be able to offer. Visit http://www.veterinarycancer.com and call them…they may be able to give you more information.
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